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Back to Journals » Diabetes, Metabolic Syndrome and Obesity » Volume 12 Dual GIP–GLP1-Receptor Agonists In The Treatment Of Type 2 Diabetes: A Short Review On Emerging Data And Therapeutic Potential Authors Bastin M , Andreelli F Received 12 May 2019 Accepted for publication 17 August 2019 Published 30 September 2019 Volume 2019:12 Pages 1973—1985 DOI Checked for plagiarism Yes Review by Single anonymous peer review Peer reviewer comments 3 Editor who approved publication: Dr Konstantinos Tziomalos Marie Bastin, Fabrizio Andreelli Diabetology-Metabolism Department, Sorbonne Université, ICAN, Assistance Publique Hôpitaux de Paris, Pitié-Salpêtrière Hospital, Paris, F-75013, France Correspondence: Fabrizio Andreelli Diabetology-Metabolism Department, Pitié-Salpêtrière Hospital, 47-83 Boulevard de l’Hôpital, Paris cedex 13, 75951, France Email [email protected] Abstract: The need for efficient and safe therapy to improve such metabolic diseases as obesity and type 2 diabetes mellitus is currently unmet

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These medications: reduce appetite lower inflammation improve liver fat improve metabolic markers reduce cardiovascular events (SELECT trial) They do not : build muscle increase VO₂ max improve mitochondrial function replace strength training fix metabolic flexibility guarantee long-term weight maintenance 2